I have created and saved a ChemDraw file sucessfully. Now after I try to make further saves to this file, a new window appears with the title "TempN" where N is the number of additional saves I have tried to make. i.e. Temp1, Temp2, etc. If I close all the windows and open the original file, none of my additions have been saved.
This is a result of Stuffit Spacesaver 5.0. You may also see this problem with other programs. The solution is to disable the Stuffit Spacesaver extension using your Extensions Manager.