I have trouble using Visual Basic, OLE and ChemDraw 4.5. I keep getting "Unable to activate object" error messages.
This problem has been fixed in an unofficial update, version 4.5.1. Ultra and Pro users can download a new 4.5.1 chemdraw.exe file. After downloading this file, double click on it to unzip it. Once unzipped simply replace the old 4.5 chemdraw.exe with the new 4.5.1 chemdraw.exe you just downloaded. Use your original 4.5 Pro or Ultra serial number during the initial launch.