Release of Columbus 2.7

Hi Everyone,

We are very excited to announce the release of Columbus^TM 2.7!

Highlights of Columbus^TM 2.7 release include the following:

• Users can search, filter, browse, and preview the Columbus database contents within High Content Profiler/Spotfire (and other clients) to directly download and aggregate cell and well level results and metadata. Users no longer need to export and import data and manually merge with metadata, saving precious time as well as avoiding mistakes during data transfer.
• Automatic triggering of batch image analysis upon image import for PerkinElmer HCS imagers including Opera Phenix and Operetta CLS.
• Enhanced Define Results Building Block
• Support for Assay Specific Building Blocks in analysis sequences
• XYZ-View for z-stacks

Your Columbus server administrator or manager should have received a notification with all the necessary information and files to upgrade your server. Please contact support (informatics.support@perkinelmer.com) if you have not received this information from PerkinElmer@flexnetoperations.com. Also, I have included the contents of our release notes below.

Seungtaek Lee | Informatics – Product Manager

PerkinElmer | For the Better

HUMAN HEALTH | ENVIRONMENTAL HEALTH

seungtaek.lee@perkinelmer.com

Supported Browsers

- Columbus fully supports:

- Firefox

- Google Chrome

- Internet Explorer 11

- Safari 5 or above

- Columbus is compatible with:

- Internet Explorer 10

- Other browsers and browser versions may function but compatibility is not guaranteed.

Known Issues

- Acapella scripts written in previous versions may not be compatible with Acapella 4.0 and Columbus 2.5. For information on how to convert old scripts to the new format refer to Technical Note 476.

- In Safari web browser, files downloaded from the links in the in the ‘Published Info’ tab may have extension .txt.csv instead of just .txt. This is automatically done by the Safari browser when it detects a file as ‘text/csv’.

Columbus 2.7.0

- Added automatic triggering of batch image analysis upon Harmony plate import by selecting a default analysis sequence for the screen (COL-1128)

- Added REST API to enable client applications to search and browse the Columbus database for direct data and metadata download (COL-975)

- Added ability to publish Screens and Plates in Columbus, in order to search, preview, and downloaded directly in High Content Profiler and TIBCO Spotfire (COL-985; COL-1085)

- Added ability to directly downloaded and merged or linked cell and well level results and assay definitions (plate layout) within High Content Profiler and TIBCO Spotfire (COL-1085)

- Added XYZ-View for z-stacks, it shows an xy-, xz- and yz-section through an image stack of a thick sample (e.g. microtissues) to allow for better interrogation of 3D image sets (COL-1156)

- Added support for Assay Specific Building Blocks in analysis sequences (COL-1157)

- Enhanced "Defined Results" Building Block for easier navigation and selection of features, including all features (COL-1159)

- The Secondary Analysis has been deprecated and might be removed in the future. It is recommended to use the High Content Profiler for the secondary analysis.

- Fixed pasting of data from Excel into concentration layer in the Assay Definition Editor (COL-1133)

- Fixed import configuration where folder names containing certain characters were not accepted (COL-274)

- Fixed Celery message queue hanging (COL-1420)

- Fix log file rotation for Columbus webapp logging (COL-1192)

- Improved default export folder name setting (COL-1444)

- Improved documentation (COL-1252, COL-1258, COL-1102, COL-405)